What makes salivary acid, the sweet "coat" of human existence, so magical?

Salivary acid is a type of infant formula ingredients sugar that is extensively present in living things and has a significant function in biology and medicine. However, many people mistake it for the acid found in "saliva," so let's learn more about this unique type of sugar today.

The sweet coat's cell surface is first, followed by salivary acid.

First, say salivary acid to put an end to a rumor. There is no clear link between salivary acid and sialic acid our saliva. Sialic acid, or Sias, is a family of negatively charged alpha keto acid monosaccharide derivatives with nine carbons. The majority of vertebrates contain it, and it is extensively spread in nature. It has a lengthy history, which is why it is known as sialic acid.

Salivary acid is the term given to a novel substance that was initially extracted from dha algal oil saliva in 1936 by scientist Gunnar Blix (Gunnar Blix) while doing investigations on the cow mandibular salivary glands in the hydrolysis of proteins.

So how does salivary acid production occur in living things? This connects to the biology lessons we received in high school. We are aware that in order to carry out complex life activities, genetic information must first pass through DNA to RNA, then from RNA to protein. In order for salivary acid to exert its biological effects in living things, it must primarily bind to proteins and lipids; this "binding" is known as salivary acid modification. Let's utilize proteins as an illustration in what follows.

Post-translated proteins must finish their glycosylation in live organisms in order to reach their full functional and mature state. This process is known as "sweet coat" glycosylation. According to recent studies, cell signaling, adhesion, and migration are significantly mediated by sialylation on the cell surface.

Additionally, life and salivary acid

We briefly discussed salivary acid in terms of basic biological facts earlier; now, let's consider how it relates to our daily lives.

salviar acid and neonatal development 1

Salivary acid and the baby brain's proper development are discovered to be tightly associated by recent studies. Brain gangliosides and glycoproteins are mostly composed of salivary acid. Brain ganglioside concentration increases around twofold between a 5-year-old toddler and a 10-week-old fetus. Similar to children, adults also require salivary acids for the development of learning and memory.

Salivary acid is now thought to be an essential nutrient for babies that supports brain development and has to be supplemented through food. Scientists have discovered that, in comparison to cow's milk, human breast milk has much more salivary acid than infant formula.

Ensuring breastfeeding is essential to supporting the proper growth and development of neonates since breast milk includes a significant quantity of salivary acid. In addition, studies on animals have shown that supplying young mice with milk powder rich in salivary acid enhances their cognitive and learning abilities.

Bird's nest with salviary acid, number two

Salivary acid is mostly present in breast milk, bird's nests, milk, eggs, and cheese in daily life. Bird nests are structures created from the condensation of a bird's down feathers or saliva released by the mucous glands in its neck. Water, fat, salivary acid, protein, and fiber are its primary chemical constituents. One of the meals with the greatest salivary acid concentration in nature, real bird's nest often has a salivary acid level of roughly 10%. Sialic acid is an anti-oxidant that prevents cell death brought on by hydrogen peroxide, fosters the creation of synapse and improves children's cognitive development, and supports the transformation of T lymphocytes and boosts immunity. Bird's nest therefore has a specific role in anti-virus, improving body immunity, and anti-aging.

Disease and Salivary Acid

The aberrant expression of salivary acid is linked to a number of disorders in addition to maintaining regular physiological activities. The pathological process of tumors, inflammation, immunity, harmful bacteria, and other disorders is now understood to include salivary acid. Let's discuss three conditions that are impacted by salivary acid below.

First, influenza

Acute respiratory illness brought on by influenza virus infection is an infectious condition that puts people's health at danger. It has been discovered that the influenza virus expresses neuraminidase on the surface (also known as salivary acid enzyme in humans and neuraminidase in microorganisms), which can catalyze the hydrolysis of salivary acid. This enzyme is crucial for maintaining the normal life cycle of influenza viruses and spreading them throughout the host. The antiviral medication oseltamivir, which is now used in clinical practice, is a neuraminidase inhibitor that can successfully stop the influenza virus from spreading throughout the human body.

Salivary acid storage illness

Sialic acid storage disease (also known as sialidosis) is an autosomal recessive genetic disorder that mostly affects people between the ages of 8 and 15 and has an incidence rate of roughly 1 in 200 000. It is brought on by gene abnormalities in salivary acid glycosidase. The accumulation of oligosaccharides in the body's cells as a result of the absence of salivary acid enzyme in the body is what causes the cherry blotch, also known as cerebellar ataxia, myoclonus, epilepsy, and the cherry red spot on the fundus of the eye. These are the main symptoms of progressive visual impairment. Cherry erythema myoclonus is another name for it.

There is currently no effective therapy for salivary acid deposition disorder, and clinical management is mostly symptomatic. Avoiding consanguineous marriage, performing a thorough prenatal diagnostic, and receiving genetic counseling are therefore crucial for individuals with a family history of the illness.

Acid-tumor indicators in serum salivary

The measurement of serum salivary acid (SA) identifies the amount of serum salivary acid present. Changes in salivary acid levels are important in identifying some disorders. With high detection rates for conditions including lung, liver, and intestine cancers (as illustrated in Figure 2), salivary acid is thought to be a generally effective tumor marker. However, excessive elevations of serum sialic acid are also linked to respiratory and cardiovascular conditions.

More and more experimental studies have discovered that salivary acid is involved in a variety of physiological and pathological processes, including human growth and development, metabolism, the occurrence of malignant tumors, etc. It also plays a critical role in the human body to maintain nitrate levels. In recent years, with the development of science and technology and the continuous improvement of medical level, scientists have gradually revealed the mystery of salivary acid for the public.

Here is a brief summary of today's lesson in the little classroom of salivary acid:

First of all, salivary acid is not an acid, and saliva has nothing to do with it. It is a substance that is found in all living things, even though it was originally isolated from saliva and given the name.

Second: Breastfeeding is healthier for newborns since it contains more sialic acid than milk powder because it is strongly tied to how an infant's nervous system develops. For adults, the meal that has the most salivary acid, which is also good for the body when consumed consistently, is bird's nest.

Third: A number of disorders, including malignant tumors, viral infections, hereditary diseases, and salivary acid storage disease, are linked to salivary acid.